A pan‐European collaboration cryed da ETERNAL project is set tae transform pharmaceutical manufacturin by reducin its environmental fitprint throu sustainable chemical an physical processes. Da initiative, dat brings tagidder saxteen pairtners frae industry, academia, an research institutes, emphasises fu life cycle approaches—frae drug design an manufacture til product disposal— for tae minimise pollution, resoorce depletion, an greenhoose gas emissions.

Da pharmaceutical industry faces growin scrutiny ower its contribution tae environmental degradation throu complex chemical syntheses, resoorce-intensive production, an waste generation. ETERNAL sikks tae address dese challenges by incorporatin green chemistry principles, mechanochemistry, an digitalisation tae optimise process performance an safety. Da project’s framewark focuses on reducin solvent yaise, enhancin resoorce recovery, an acceleratin process optimisation while ensurin compliance wi evolvin environmental regulations.

Quotient Sciences, a key pairtner in da consortium, is leveragin its expertise in digitalisation as pairt o da ETERNAL project. Deir wark includes developin Digital Twins tae simulate an optimise processes. Dese digital representations aim tae reduce laboratory experimentation by allouin virtual experiments dat consume fewer reagents an solvents. As stated in da project documents, Quotient Sciences “aims tae reduce da nummer o experiments required at da laboratory or pilot scale, dereby minimisin resoorce consumption an waste generation.” Deir approach nae ainly streamlines da scale-up o active pharmaceutical ingredient synthesis but provides real-time monitorin, reducin da risk o deviations an waste.

Da Digital Twin technology developed by Quotient Sciences is a central component o da project’s strategy tae improve process efficiency an environmental performance. By enablin a reduction in physical experiments, da technology supports a mair sustainable approach tae drug development an manufacturing. Dis innovation is reflective o da braider industry move tae integrated solutions dat prioritise baith environmental an economic benefits. Da decreasin need for extensive lab-scale experimentation has da potential tae significantly cut emissions an reduce da yaise o hazardous chemicals.

Da ETERNAL project addresses hazardous waste management, da environmental risks associated wi active pharmaceutical ingredients, an da adoption o a circular economy model in manufacturing. Da initiative encourages da yaise o renewable feedstocks, energy-efficient processes, an real-time analysis an monitorin for tae foster safer, mair efficient operations.

As regulatory demands increase an societal expectations for environmental responsibility intensify, da collaborative efforts ithin ETERNAL unnerline an industry-wide commitment tae achieve sustainable pharmaceutical manufacturing. Da project’s integrated approach micht serve as a blaeprint for idder global companies sikkin tae reduce deir environmental impact while maintainin heich product quality an operational efficiency.